376: Antithrombin for Heparin Resistance in Patients Without Mechanical Circulatory Support Devices
نویسندگان
چکیده
منابع مشابه
Antithrombin III Deficiency in Patients Requiring Mechanical Circulatory Support
Introduction: Antithrombin or antithrombin III is a vitamin K-independent, natural anticoagulant that is the major inhibitor of thrombin. With the binding of heparin, a conformational change in antithrombin occurs that increases the inactivation of thrombin by antithrombin by 4000-fold. Antithrombin deficiency can be hereditary or acquired; the acquired form is frequently encountered in patient...
متن کاملNew devices for pediatric mechanical circulatory support.
PURPOSE OF REVIEW In adult patients with advanced heart failure, mechanical circulatory support devices (MCSDs) offer a valid treatment option. MCSDs can serve as a bridge to transplant, bridge to recovery or destination therapy. In the REMATCH trial, MCSDs outperformed medical management for long-term support of end-stage heart failure. Until recently, pediatric patients could not fully benefi...
متن کاملHistory of Mechanical Circulatory Support Devices
History of Mechanical Circulatory Support Devices Advanced heart failure (HF) is a major cause of morbidity and mortality in the United States, and heart transplantation remains as the gold standard therapy. Because of scarcity of donor organs, the application of mechanical circulatory support devices has become a crucial approach in HF therapy as a bridge to transplantation. Therefore, mechani...
متن کاملMechanical Circulatory Support Devices for Acute Right Ventricular Failure.
Right ventricular (RV) failure remains a major cause of global morbidity and mortality for patients with advanced heart failure, pulmonary hypertension, or acute myocardial infarction and after major cardiac surgery. Over the past 2 decades, percutaneously delivered acute mechanical circulatory support pumps specifically designed to support RV failure have been introduced into clinical practice...
متن کاملCurrent Mechanical Circulatory Support Devices for End Stage Heart Failure
Mechanical circulatory support is necessary when heart failure becomes refractory to medical support. It is typically instituted when organ dysfunction occurs as a result of hypoperfusion. Enthusiasm has recently developed for the role of mechanical circulatory support in the ever-growing population of heart failure patients. Indeed, efforts in developing this technology have allowed for the re...
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ژورنال
عنوان ژورنال: Critical Care Medicine
سال: 2020
ISSN: 0090-3493
DOI: 10.1097/01.ccm.0000727392.51307.86